
Science fiction TV has a history of pushing boundaries and sparking imagination, but crafting a satisfying final episode is notoriously difficult. Because these shows often build complex worlds and storylines, finales can sometimes feel hurried or unclear. For streaming services like Prime Video, a strong series ending is especially important for keeping viewers engaged over the long run.
Even though TV shows don’t always get proper endings, several sci-fi series on Prime Video have managed to deliver truly satisfying finales. These shows weren’t just enjoyable from the beginning; they also wrapped up their stories in a way that felt true to their core ideas, treated their characters well, and stayed with viewers long after they finished watching.
The Man In The High Castle (2015–2019)
Series Finale: “Fire From The Gods”

Based on Philip K. Dick’s novel, The Man in the High Castle explores themes of fascism, rebellion, and what defines a culture. The four-season show is set in an alternate history where Germany and Japan won World War II.
The series finale fully explores the idea of the multiverse, proving that many alternate worlds exist with different pasts. In the very last scene, a gateway opens, letting people from these other realities enter the main world of the show.
Though the show’s ending sparked debate among viewers, critics praised it for staying true to the series’ underlying ideas. Rather than offering a simple, dramatic resolution, the finale focused on deeper themes and symbolism, fitting with the show’s overall exploration of power and personal choice.
The Second Best Hospital In The Galaxy (2024–2025)
Series Finale: “Sedate That Tentacle!”

Despite receiving a very high 94% score from critics on Rotten Tomatoes, the animated series The Second Best Hospital in the Galaxy didn’t initially attract a large audience. This adult sci-fi comedy follows alien doctors Sleech and Klak, using outlandish medical situations in space to thoughtfully examine complex emotions and moral questions.
The show lasted two seasons, and the second season of The Second Best Hospital in the Galaxy was even better than the first. Critics liked how the show developed its characters and made the emotional moments more impactful. The finale focused on two main storylines: Sleech dealing with painful memories and facing the results of her past actions, and Klak finally understanding who she is.
This episode skillfully mixes the show’s silly, offbeat comedy with genuinely heartfelt moments for the characters. The ending felt complete and meaningful – something you don’t often see in adult animated sci-fi comedies – and reviewers praised the series for concluding on its own terms instead of being stretched out indefinitely.
Undone (2019–2022)
Series Finale: “We All Love Each Other”

Undone is an animated sci-fi drama that uses a unique technique called rotoscoping, where animation is traced over live-action footage. It’s a genre-bending show, mixing psychological drama with elements of magical realism. The story centers on Alma, who grapples with family issues, past trauma, and figuring out who she is, all while discovering she can manipulate time. This ability lets her change events in her family’s history, essentially rewriting the past.
In the final episode, Alma realizes she’s lost her power over time and starts to understand the personal cost of her actions. She’s forced to accept the boundaries of what she can do and deal with the emotional impact her changes have had on the people she cares about.
The show’s ending, rather than tying up all loose ends, fits with its overall themes of memory and who we are. It’s emotionally resonant without pretending to have easy answers. This balance between unresolved questions and strong character development makes it one of the best sci-fi series finales on Prime Video.
Tales from the Loop (2020)
Series Finale: “Home”

Tales from the Loop is a unique science fiction series that stands out by focusing on characters’ feelings rather than typical sci-fi action. Inspired by the art of Simon Stålenhag, the show takes place in a town built over a strange, high-tech research center called ‘the Loop,’ and explores how this technology impacts people’s lives.
Rather than tying up every storyline, the finale wisely concentrates on how the season’s ideas affected the characters’ feelings. The story of the main family specifically explores the show’s bigger themes about time – how it can damage relationships and leave people stuck in the past.
Reviewers applauded the finale of Tales from the Loop for maintaining its thoughtful and reflective mood, rather than relying on typical science fiction clichés or surprises. While the show featured elements like time travel and altered realities, it ultimately focused on meaningful human decisions. The ending felt powerful because it reflected the uncertainties, brief experiences, and emotional resolutions found in real life.
The Expanse (2015–2022)
Series Finale: “Babylon’s Ashes”
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Based on the novels by James S. A. Corey, The Expanse is a critically acclaimed science fiction series. It’s set in the future, after humans have settled throughout our solar system, and expertly combines political maneuvering, realistic science, and compelling stories that span planets and the asteroid belt.
Rather than quickly covering the rest of the book’s plot, the show’s final season focused on bringing the conflict with Marco Inaros and the Free Navy to a satisfying conclusion. This allowed the story to develop naturally towards a powerful and well-deserved showdown, instead of feeling rushed.
As the story ends, humanity has finally achieved a fragile peace and looks forward to a future of exploration. Holden grapples with the weight of leadership in a broken world, Naomi finds resolution in her difficult choices between personal feelings and what’s right, Amos demonstrates how hard-won survival can be softened by trust, and Drummer’s experiences highlight the sacrifices required to bring people together in a fractured society.
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2025-12-30 00:00